PREEMPT 1 and 2 Subject Portal

So I finally finished my assignment for Information Discovery, the subject portal on the use of BOTOX for Chronic Migraine. I definitely learned a lot, most of all that I'm very grateful that I don't get Chronic Migraines. The research was fun, and interesting, but I found it more difficult when it came to writing my critically annotated bibliography. Because the articles are all on the same subject, I was repeating myself quite a lot and I began to hate certain phrases that I was using. It was hard to write them all, I could get distracted by absolutely everything around me.

The final list of fifteen sources focusses on the PREEMPT studies, and the studies that resulted from it. I also included journal articles that looked at the injection paradigm, the placebo effect, and the complicating issue of medication overuse headaches. For the sake of variety I found a press release from Allergan and the application to the PBS for the use of BOTOX for Chronic Migraine. My lecturer wanted us to show a range of sources, which was difficult for me. Because my topic was quite specialised, all I was finding were journal articles, and so I used MedNar to find some different types of sources.

Here's my list of the fifteen sources that I used. They aren't in alphabetical order; there is an order to it, but it's my own system. The first four are the original PREEMPT studies, then the injection method that resulted from the studies, then the issue of medication overuse headache. Then there are more general articles on Chronic Migraine, including the economic costs. Finally, the 'just there for the sake of variety' articles - one from Allergan, two by the government.

1. Aurora, S.K., Dodick, D.W., Turkel C.C., ReGryse, R.E., Silberstien, S.D., Lipton, R.B., Diencer, H.C., and Brin, M.F., on behalf of the PREEMPT I Chronic Migraine Study Group 2010, 'OnabotulinumtoxinA for Treatment of Chronic Migraine: Results From the Double-Blind, Randomised, Placebo-Controlled Phase of the PREEMPT I Trial', Cephalalgia, vol.30, no.7, pp793-803
2. Diener, H.C., Dodick, D.W., Aurora S.K., Turkel, C.C., DeGryse, R.E., Lipton, R.B., Silberstein, S.D., Brin, M.F., on behalf of the PREEMPT 2 Chronic Migraine Study Group 2010, 'OnabotulinumtoxinA for Treatment of Chronic Migraine: Results From the Double-Blind, Randomised, Placebo-Controlled Phase of the PREEMPT 2 Trial,' Cephalalgia, vol.30, no.7, pp804-814
3. Dodick, David W., Turkel, Catherine C., DeGryse, Ronald E., Aurora, Sheena K., Silberstein, Stephen D., Lipton, Richard B., Diener, Hans-Cristoph, Brin, Mitchell F. 2010, 'OnabotulinumtoxinA for Treatment of Chronic Migraine: Pooled Results From the Double-Blind, Randomised, Placebo-Controlled Phases of the PREEMPT Clinical Program', Headache: The Journal of Head and Face Pain, vol.50, no.6, pp921-936
4. Aurora, S.K., Dodick, D.W., Diener, H-C., DeGryse, R.E., Turkel, C.C., Lipton, R.B., Silberstein, S.D. 2014, 'OnabotulinumtoxinA for Chronic Migraine: Efficacy, Safety, and Tolerability in Patients Who Received All Five Treatment Cycles in the PREEMPT Clinical Program, Acta Neurol Scan, vol.129, no.1, pp61-70
5. Liberini, P., Pari, E., Gazzina, S., Caratozzolo, S., Rao, R., Padovani, A. 2014, 'Technique of Injection of OnabotulinumtoxinA for Chronic Migraine: the PREEMPT Injection Paradigm', Neurological Sciences, Supplement 35, pp41-3.
6. Blumenfeld, Andrew, Silberstein, Stephen D., Dodick, David W., Aurora, Sheena K., Turkel, Catherine C., Binder, William J. 2010, 'Method of Injection of OnabotulinumtoxinA for Chronic Migraine: A Safe, Well-Tolerated, and Effective Treatment Paradigm Based on the PREEMPT Clinical Program', Headache: The Journal of Head and Face Pain, vol.50, no.9, pp1406-1418
7. Negro, Andrea and Martelletti 2011, 'Chronic Migraine Plus Medication Overuse Headache: Two Entities or Not?', The Journal of Headache and Pain, vol.12, no.6., pp593-601
8. Silberstein, Stephen D., Blumenfeld, Andrew M., Cady, Roger K., Turner, Ira M., Lipton, Richard B., Diener, Hans-Cristoph, Aurora, Sheena K., Sirimanne, Mai, DeGryse, Ronald E., Turkel, Catherine C., Dodick, David W. 2013, 'OnabotulinumtoxinA for Treatment of Chronic Migraine: PREEMPT 24-Week Pooled Subgroup Analysis of Patients Who had Acute Medication Overuse at Baseline', Journal of the Neurological Sciences, vol.331, nos.1-2, pp48-56
9. Lanteri-Minet, Michel 2013, 'Economic Burden and Costs of Chronic Migraine', Current Pain and Headache Reports, vol.18, no.1, pp1-6
10. Dougherty, Carrie and Silberstein, Stephen D. 2014, 'Providing Care for Patients with Chronic Migraine: Diagnosis, Treatment, and Management, Pain Practice
11. Lipton, Richard B. and Silberstein, Stephen D. 2015, 'Episodic and Chronic Migraine Headache: Breaking Down Barriers to Optimal Treatment and Prevention', Headache: The Journal of Head and Face Pain, vol.55, supp.S2, pp103-122
12. Solomon, Seymour 2011, 'Botulinum Toxin for the Treatment of Chronic Migraine: The Placebo Effect', Headache: The Journal of Head and Face Pain, vol.51, no.6, pp980-985
13. Allergan 2010, BOTOX(R) (onabotulinumtoxinA) FDA Approved as Prophylactic Treatment Option for Adult Chronic Migraine Sufferers, Allergan Inc.
14. Australian Government Department of Health 2013, 1168 - Injection of Botulinum Toxin (Botox) for Prophylaxis of Headaches in Adults with Chronic Migraine
15. Australian Government Department of Health, The Pharmaceutical Benefits Scheme 2013, Botulinum Toxin Type A, Injection, 100 units/vial, Botox (R) - July 2013